Gut & Digestion + Grass-Fed Colostrum + Histamine & Immune

Digestive Stack

POWERFUL SUPPORT FOR A HEALTHY GUT.

HEALTH GOAL

DIGESTIVE HEALTH

This stack is ideal for those seeking to optimize gut and digestive health, and provides comprehensive nutritional support for a strong and healthy gut.

  • 1x Gut & Digestion
  • 1x Grass-Fed Colostrum
  • 1x Histamine & Immune
Delivers

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IS THE DIGESTIVE STACK FOR ME?

This stack is ideal for those seeking to optimize gut and digestive health, and provides comprehensive nutritional support for a strong and healthy gut.

I can tell a huge difference in my digestion and in the amount of energy
I have throughout the day.

Janine H.

Verified Customer

WHAT'S IN THE STACK?

digestive_stack
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Primary

Gut & Digestion

Gut & Digestion is the foundational supplement included in the Digestive Stack. It provides unique and essential support found in grass-fed and grass-finished tripe (stomach), intestines, pancreas, liver, and spleen.

Organ Nutrients

Tripe is a robust source of the mineral manganese, and dietary manganese can decrease intestinal permeability and enhance microbiota composition.

Liver is the single most nutritious natural food on the planet, both in terms of density and variety. It is incredibly rich in vitamins, minerals, peptides and enzymes to support immune, reproductive, digestive, musculoskeletal, and nervous health.

Pancreas contains enzymes such as amylase, lipase, and trypsin, as well as B5, B12, and selenium to support digestion and the gut microbiome.

Intestines are rich in a wide range of peptides, enzymes, vitamins and minerals that support optimal gut health and digestion. Their mucosal lining contains compounds aiding in nutrient absorption and barrier protection.

Spleen has high levels of heme iron, the most bioavailable form of iron, to support the nervous system and immune health. It is also rich in niacin, which is crucial for metabolic health, and selenium, a key player in thyroid function.

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REVITALIZE YOUR GUT

Try the Stack
Digestive Stack

POWERFUL NUTRIENTS

The combined power of Gut & Digestion, Grass-Fed Colostrum, and Histamine & Immune
includes essential nutrients.

Alpha defensins 5 and 6

Antimicrobial peptides involved in the immune response.

Gastrin-releasing Peptide

Also known as GPR, this peptide is found in pancreatic tissue and supports digestive processes by stimulating the release of enzymes, bicarbonate, and fluids.

Manganese

A vital mineral involved in antioxidant defense (Super Oxide Dismutase), thyroid function, bone health, blood sugar regulation, as well as wound healing and collagen production.

Selenium

A critical mineral for thyroid function (iodothyronine deiodinanses) and immune health/antioxidant defense (glutathione peroxidase, thioredoxin reductase).

B12

Necessary for proper cell division, red blood cell production, neurotransmitter formation, and optimal exercise performance.

Hepcidin Peptide

A peptide directly involved in iron metabolism as well as the innate immune response.

Splenin, Tuftsin and Splenopentin Peptides

Exclusively found in splenic tissue which enhances immune function.

Ergothioneine Peptide

An amino acid found in liver, kidney, and bone marrow found to support detoxification and longevity pathways.

Liver Expressed Antimicrobial Peptide

Also known as LEAP-2. This peptide is involved in immune response and glucose metabolism.

Niacin

A B3 vitamin essential for cardiovascular health, mood, cognition, and energy.

Copper, biotin, and CoQ10

Crucial for metabolism, mood, and energy, as well as the health of skin, hair, and nails.

Riboflavin, folate, and choline

Essential for red blood cell formation, brain, reproductive, and cardiovascular health.

Vitamins A, D, E, K2

Get these vitamins in a super bioavailable form that play critical roles in overall immune and bone health.

Lipase, Protease, and Amylase

Enzymes to help break down macronutrients like fat, protein and carbohydrates.

Colipase, Trypsin, and Pancreatic Peptide

Support the activation of enzymes needed to break down protein and help with food allergies by improving digestion.

Immunoglobulins (IgA, IgG, IgM, IgD, IgE)

Antibodies that play an integral role in immune defense mechanisms.

Transforming Growth Factors - Alpha & Beta (TGF-a & b)

Stimulates growth and differentiation of various connective tissue, including bone and cartilage, and is crucial for wound healing, gut healing, as well as DNA synthesis and repair.

Proline-rich Polypeptides (PRPs), like Colostrinin

Crucial for thymus gland support (command center for immune defense), growth and differentiation of B lymphocytes, and modulating the immune response.

Insulin-like Growth Factor- I & II (IGF-I & -II)

Found abundantly in colostrum and helps balance blood sugar, increase HDL, build lean muscle, and aids in the metabolism of protein, fat, and carbs.

Lactoferrin

Crucial iron-binding protein which helps starve bacteria of iron needed to reproduce and modulates a powerful immune response to invading organisms.

Epithelial Growth Factor (EGF)

Crucial for skin health and wound healing.

Colony-stimulating Factor-1 (macrophage colony-stimulating factor)

Stimulates stem cells to differentiate into macrophages — immune cells that "eat" or clean up dead pathogens/debris from inflammation and infection.

Cytokines, Interleukins, Interferons, and Lymphokines

Cell signaling molecules crucial for balancing inflammation and boosting T cell activity as well as the production of antibodies. These communication molecules have been identified as important molecules for treatment of cancer, pain, and various diseases.

Lactalbumins

Identified through research to induce selective apoptosis (cell death) of cancer cells and highly effective against various viruses.

Thymopoietin and Thymulin

Essential peptides for immune cell programming and activation of the immune system.

Diamine Oxidase (DAO)

Supports overall immune health, histamine metabolism, and digestion.

Thymosin fraction 5 and thymosin alpha-1

Peptides that are potent stimulators of the immune system and enhance immune cell functioning.

Thymosin beta-4

Important peptide in stimulating pituitary hormones essential for reproductive function.

Thymic humoral factor

Increases the immune response, especially to viruses.

Kidney-specific peptides

Reduce the concentration of oxalates in the urine and calcium deposits in the renal tissue, as well as preventing free-radical induced damage.

Bovine Beta-Defensins and Cathelicidins

Peptides known to have broad antimicrobial roles in the body.

Heme iron

Crucial for brain health, energy, and exercise performance, as well as immune function.

I can feel my entire system getting a reboot from these amazing supplements.

Jaclyn F.

Verified Customer

Digestive Stack

  • 1x Gut & Digestion
  • 1x Grass-Fed Colostrum
  • 1x Histamine & Immune
Delivers

Free U.S. shipping over $80

HEART & SOIL 101

  • How to Use

    Take 6 capsules, once daily, of each supplement. If you’re new to taking organ supplements, start with 1-2 capsules of each daily for the first week before increasing by one capsule daily. Consistent long-term use provides the best results.

  • Benefits

    Our Digestive Stack aims to optimize gut and digestive health, and provides comprehensive nutritional support for a strong and healthy gut.

  • Quality

    Rigorous third-party testing by independent labs during and after manufacturing. Quality and purity information can be provided upon request.

  • Dietary

    100% additive, hormone, allergen, antibiotic, pesticide, and GMO-free. Freeze-dried. Pure nose-to-tail nourishment.

Digestive Stack Questions

This stack is ideal for anyone struggling with gastrointestinal and digestive issues, providing comprehensive nutritional support for a strong and healthy gut.

The combination of products in this stack work synergistically to deliver a wide range of highly bioavailable Vitamins, Minerals, Peptides, and Essential Fatty Acids that rejuvenate your gut, supporting both digestive function and a healthy immune response.

MORE QUESTIONS? WE'D BE HAPPY TO HELP.

Frequently Asked Questions

CUSTOMER REVIEWS

Customer Reviews
4.8 Based on 20 Reviews
5 ★
95% 
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Filter Reviews:
S
03/29/2025
Sarah SVG verified by SHOP
United States

I have tried numerous supplements and brands. I am extremely pick about the quality and sourcing of the vitamin. I will stick with this one.

E
03/03/2025
Ester SVG verified by SHOP
United States

No scent or aftertaste. Capsules are easy to swallow. I had the Joints and the Kidney fat previously and my body was recovering nicely, post training and performance injuries.

E
02/07/2025
Ezmeralda SVG verified by SHOP
United States

Amazing products 🙌�

C
02/03/2025
Christina
United States

No more bloating!!

I gradually increased my dose to full recommended dosing over the course of about a month. I take half with breakfast and half with lunch. I have almost no bloating, my mode has leveled, and rarley have any GI symptoms. Just reordered my 2nd regimen!

AN
01/27/2025
Andrew N.
United States

Okay, but not for me

My wife absolutely loves them, and they work great for her. For me however, I cannot take them without negative side effects. Started off with 1 pill every 2 days and the stomach pains and nausea kept getting worse and worse.... Stopped taking it and everything resolved. Works great for some, and not great for others. If you got gut issues recommend starting very slowly to see if you can handle it. Cheers hope this review helps you.

01/29/2025

Heart & Soil Supplements

Hey Andrew, Thanks for sharing your honest experience! We’re so glad to hear that your wife is loving the supplements and seeing great results. At the same time, we completely understand that everyone’s body responds differently. When it comes to those dealing with gut imbalances or other sensitivities, it can be helpful to start with our most simple formulation: Pure American Liver. This is a great way to introduce organs gradually and ease into the benefits in a more gentle way. We appreciate you taking the time to leave this review. If you ever decide to try again or want any guidance on how to better tolerate them, feel free to reach out to our Health Success team at radicalhealth@heartandsoil.co—we’re always happy to help! Cheers, and thanks again for your thoughtful feedback. The Heart and Soil Team

Disclaimer: The testimonials on this page reflect the personal experiences of individual customers and may not represent typical results. Our products are intended to support overall health and well-being. We do not claim to cure or treat any specific diseases or conditions. If you have any health concerns, please consult with a healthcare professional. Do not replace prescribed medications without consulting your doctor.

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