500mg / 180 capsules

Histamine & Immune

Strengthen your defenses.

Our Histamine & Immune supplement is packed with vital nutrients and peptides to provide support for the immune system, histamine intolerance, and allergies.

  • Made with grass-fed thymus, lung, spleen, liver, and kidney
  • Stimulates your immune fighting cells to defeat viruses and pathogens
  • Strategic immune support
Delivers

No commitment subscription. Change or cancel anytime.

Save 10% (average subscriber saves $180+ per year)

Become a part of our tribe: exclusive content, deals, and more

Free & easy returns

Free U.S. shipping over $80

154,186+ Happy customers

See all reviews

INFORMED SPORT CERTIFIED

Our products meet the highest quality standards possible for vitamins and supplements. Each batch of Histamine & Immune is tested by Informed Sport, a globally recognized substance testing certification program considered to be the gold standard for quality assurance of sports nutrition around the world.

Rigorous Sport Testing

Histamine & Immune has been tested against prohibited substance lists from WADA, NHL, MLS, PGA/LPGA, and NCAA. Testing includes over 200+ prohibited substances in sports.

Uncompromising Quality

Informed Sport tests each and every batch of Histamine & Immune. There are no composite tests. They are always tested individually to ensure this standard of excellence.

Globally Recognized

Informed Sport is recognized by sporting organizations, antidoping agencies, athletes, and supplement users worldwide.

Benefits of Daily Use

Set yourself up for success by ensuring you never miss a bottle.

  • Enhance immune cell functioning

  • Response to pathogens

  • Overall immune health

  • Histamine metabolism

475+ 5-Star Reviews

Key nutrients, peptides, and growth factors For your immune system

Thymopoietin and Thymulin

Essential peptides for immune cell programming and activation of the immune system

Diamine Oxidase (DAO)

Supports overall immune health, histamine metabolism, and digestion.

Thymosin fraction 5 and thymosin alpha-1

Peptides that are potent stimulators of the immune system and enhance immune cell functioning.

Liver Expressed Antimicrobial Peptide

Also known as LEAP-2. This peptide is involved in immune response and glucose metabolism.

Thymosin beta-4

Important peptide in stimulating pituitary hormones essential for reproductive function.

Hepcidin Peptide

A peptide directly involved in iron metabolism as well as the innate immune response.

Thymic humoral factor

Increases the immune response, especially to viruses.

Kidney-specific peptides

Reduce the concentration of oxalates in the urine and calcium deposits in the renal tissue, as well as preventing free-radical induced damage.

Bovine Beta-Defensins and Cathelicidins

Peptides known to have broad antimicrobial roles in the body.

Vitamins A, D, E, K2

Get these vitamins in a super bioavailable form that play critical roles in overall immune and bone health.

Splenin, Tuftsin and Splenopentin Peptides

Peptides exclusively found in splenic tissue which enhance immune function.

Riboflavin, Folate, B12, and Choline

Essential for red blood cell formation, brain, reproductive, and cardiovascular health.

Heme iron

Crucial for brain health, energy, and exercise performance, as well as immune function.

Copper, Biotin, and CoQ10

Crucial for metabolism, mood, and energy, as well as the health of skin, hair, and nails.

Niacin

A B3 vitamin essential for cardiovascular health, mood, cognition, and energy.

Selenium

A critical mineral for thyroid function (iodothyronine deiodinanses) and immune health/antioxidant defense (glutathione peroxidase, thioredoxin reductase).

Ergothioneine Peptide

An amino acid found in liver, kidney, and bone marrow found to support detoxification and longevity pathways.

Thymopoietin and Thymulin

Essential peptides for immune cell programming and activation of the immune system

Diamine Oxidase (DAO)

Supports overall immune health, histamine metabolism, and digestion.

Thymosin fraction 5 and thymosin alpha-1

Peptides that are potent stimulators of the immune system and enhance immune cell functioning.

Liver Expressed Antimicrobial Peptide

Also known as LEAP-2. This peptide is involved in immune response and glucose metabolism.

Thymosin beta-4

Important peptide in stimulating pituitary hormones essential for reproductive function.

Hepcidin Peptide

A peptide directly involved in iron metabolism as well as the innate immune response.

Thymic humoral factor

Increases the immune response, especially to viruses.

Kidney-specific peptides

Reduce the concentration of oxalates in the urine and calcium deposits in the renal tissue, as well as preventing free-radical induced damage.

Bovine Beta-Defensins and Cathelicidins

Peptides known to have broad antimicrobial roles in the body.

Vitamins A, D, E, K2

Get these vitamins in a super bioavailable form that play critical roles in overall immune and bone health.

Splenin, Tuftsin and Splenopentin Peptides

Peptides exclusively found in splenic tissue which enhance immune function.

Riboflavin, Folate, B12, and Choline

Essential for red blood cell formation, brain, reproductive, and cardiovascular health.

Heme iron

Crucial for brain health, energy, and exercise performance, as well as immune function.

Copper, Biotin, and CoQ10

Crucial for metabolism, mood, and energy, as well as the health of skin, hair, and nails.

Niacin

A B3 vitamin essential for cardiovascular health, mood, cognition, and energy.

Selenium

A critical mineral for thyroid function (iodothyronine deiodinanses) and immune health/antioxidant defense (glutathione peroxidase, thioredoxin reductase).

Ergothioneine Peptide

An amino acid found in liver, kidney, and bone marrow found to support detoxification and longevity pathways.

Histamine & Immune 101

  • How to Use

    Take six capsules once daily. It’s that easy. If you’re new to taking organ supplements, start with 1-2 capsules daily for the first week before increasing by one capsule daily. Consistent long-term use produces the best results. Ask us if you need help.

  • Benefits

    Histamine & Immune provides nutritional support to reduce itchy/watery eyes, improve immune response to pathogens (bacteria, viruses, parasites, mold), and histamine intolerance.

  • Quality

    Rigorous third-party testing by independent labs during and after manufacturing. Quality and purity information can be provided upon request.

  • Dietary

    100% Additive, hormone, allergen, antibiotic, pesticide & GMO-free. Freeze-dried. Pure nose-to-tail nourishment.

Trusted

Heart & Soil was founded by Paul Saladino, MD. He’s helped tens of thousands of people reclaim their health through an animal-based diet. He pours his heart into Heart & Soil. You’ll feel the difference.

Our Story

They love Histamine & Immune

Why Heart & Soil

Want to keep researching?

GET EXPERT SUPPORT

Connect with our Health Success Team today for personalized guidance and support.

Connect with us

Get weekly health insights delivered to your inbox so you can radically improve your health

Join 155,000+ Subscribers

Histamine & Immune

495 reviews