-
Improve your gut health
-
Solve leaky gut
-
Improve digestive issues
-
Improve autoimmune illnesses
500mg / 180 capsules
Gut & Digestion
Heal your gut.
Our Gut & Digestion supplement is packed with critical nutrients and peptides to provide support for leaky gut, digestive issues, and autoimmune illness.
- Grass-fed & finished tripe (stomach), intestines, pancreas, liver, and spleen
- Improved nutrient absorption compared to synthetic alternatives
- Strategic support for gut inflammation and digestion
154,186+ Happy customers
See all reviewsINFORMED SPORT CERTIFIED
Our products meet the highest quality standards possible for vitamins and supplements. Each batch of Gut & Digestion is tested by Informed Sport, a globally recognized substance testing certification program considered to be the gold standard for quality assurance of sports nutrition around the world.
Rigorous Sport Testing
Gut & Digestion has been tested against prohibited substance lists from WADA, NHL, MLS, PGA/LPGA, and NCAA. Testing includes over 200+ prohibited substances in sports.
Uncompromising Quality
Informed Sport tests each and every batch of Gut & Digestion. There are no composite tests. They are always tested individually to ensure this standard of excellence.
Globally Recognized
Informed Sport is recognized by sporting organizations, antidoping agencies, athletes, and supplement users worldwide.
Benefits of Daily Use
Set yourself up for success by ensuring you never miss a bottle.
Critical Nutrients, Peptides, and Growth factors in one powerful supplement
Alpha defensins 5 and 6
Antimicrobial peptides involved in the immune response.
Gastrin-releasing Peptide
Also known as GPR, this peptide is found in pancreatic tissue and supports digestive processes by stimulating the release of enzymes, bicarbonate, and fluids.
Manganese
A vital mineral involved in antioxidant defense (Super Oxide Dismutase), thyroid function, bone health, blood sugar regulation, as well as wound healing and collagen production.
Selenium
A critical mineral for thyroid function (iodothyronine deiodinanses) and immune health/antioxidant defense (glutathione peroxidase, thioredoxin reductase).
B12
Necessary for proper cell division, red blood cell production, neurotransmitter formation, and optimal exercise performance.
Hepcidin Peptide
A peptide directly involved in iron metabolism as well as the innate immune response.
Splenin, Tuftsin and Splenopentin Peptides
Exclusively found in splenic tissue which enhances immune function.
Ergothioneine Peptide
An amino acid found in liver, kidney, and bone marrow found to support detoxification and longevity pathways.
Liver Expressed Antimicrobial Peptide
Also known as LEAP-2. This peptide is involved in immune response and glucose metabolism.
Niacin
A B3 vitamin essential for cardiovascular health, mood, cognition, and energy.
Copper, biotin, and CoQ10
Crucial for metabolism, mood, and energy, as well as the health of skin, hair, and nails.
Riboflavin, folate, B12, and choline
Essential for red blood cell formation, brain, reproductive, and cardiovascular health.
Vitamins A, D, E, K2
Get these vitamins in a super bioavailable form that play critical roles in overall immune and bone health.
Lipase, Protease, and Amylase
Enzymes to help break down macronutrients like fat, protein and carbohydrates.
Colipase, Trypsin, and Pancreatic Peptide
Support the activation of enzymes needed to break down protein and help with food allergies by improving digestion.
Alpha defensins 5 and 6
Antimicrobial peptides involved in the immune response.
Gastrin-releasing Peptide
Also known as GPR, this peptide is found in pancreatic tissue and supports digestive processes by stimulating the release of enzymes, bicarbonate, and fluids.
Manganese
A vital mineral involved in antioxidant defense (Super Oxide Dismutase), thyroid function, bone health, blood sugar regulation, as well as wound healing and collagen production.
Selenium
A critical mineral for thyroid function (iodothyronine deiodinanses) and immune health/antioxidant defense (glutathione peroxidase, thioredoxin reductase).
B12
Necessary for proper cell division, red blood cell production, neurotransmitter formation, and optimal exercise performance.
Hepcidin Peptide
A peptide directly involved in iron metabolism as well as the innate immune response.
Splenin, Tuftsin and Splenopentin Peptides
Exclusively found in splenic tissue which enhances immune function.
Ergothioneine Peptide
An amino acid found in liver, kidney, and bone marrow found to support detoxification and longevity pathways.
Liver Expressed Antimicrobial Peptide
Also known as LEAP-2. This peptide is involved in immune response and glucose metabolism.
Niacin
A B3 vitamin essential for cardiovascular health, mood, cognition, and energy.
Copper, biotin, and CoQ10
Crucial for metabolism, mood, and energy, as well as the health of skin, hair, and nails.
Riboflavin, folate, B12, and choline
Essential for red blood cell formation, brain, reproductive, and cardiovascular health.
Vitamins A, D, E, K2
Get these vitamins in a super bioavailable form that play critical roles in overall immune and bone health.
Lipase, Protease, and Amylase
Enzymes to help break down macronutrients like fat, protein and carbohydrates.
Colipase, Trypsin, and Pancreatic Peptide
Support the activation of enzymes needed to break down protein and help with food allergies by improving digestion.
Gut & Digestion 101
-
How to Use
Take six capsules once daily. It’s that easy. If you’re new to taking organ supplements, start with 1-2 capsules daily for the first week before increasing by one capsule daily. Consistent long-term use produces the best results. Ask us if you need help.
-
Benefits
Gut & Digestion provides targeted gut support to help eliminate bloating, reduce inflammation, and ensure proper digestive functions.
-
Quality
Rigorous third-party testing by independent labs during and after manufacturing. Quality and purity information can be provided upon request.
-
Dietary
100% Additive, hormone, allergen, antibiotic, pesticide & GMO-free. Freeze-Dried. Pure nose-to-tail nourishment.
Trusted
Heart & Soil was founded by Paul Saladino, MD. He’s helped tens of thousands of people reclaim their health through an animal-based diet. He pours his heart into Heart & Soil. You’ll feel the difference.
Our StoryThey love Gut & Digestion
Customer Reviews
4.7 Based on 628 Reviews
Customer Photos
- Reviews
- Questions
Filter Reviews:
- digestion
- supplements
- difference
- diet
- issues
- Heart
- life
- Paul
- Soil
- energy
Loading more...
L
02/28/2025
Lisa
United States
The Heartburn finally went away!
I have been struggling with heartburn for 30 years. I have tried everything natural I could find to stop it. Last year I started eating a Keto and Carnivore diet, and while the heartburn issues improved, they still did not go away completely. I started taking Gut & Digestion about 2 weeks ago, and a few days ago I realized all of the heartburn symptoms are completely gone!
K
02/16/2025
Krista
United States
Cure for Microscopic Colitis!
I rarely review supplements. Just purchased my second bottle. This supplement cured my microscopic colitis. The doctor recommended steroids, but I kept searching for something natural. After 6 months of googling, I found this… it works. I hope this helps someone else looking for help.
02/18/2025
Heart & Soil Supplements
Hi Krista, Thank you so much for sharing your experience with us. We're so happy to hear how our Gut & Digestion has been supportive in your journey of healing your microscopic colitis, that is truly amazing! Stories like yours inspire us to keep doing what we do. We truly appreciate your support and hope this continues to be a game-changer for you! All the best, The Heart and Soil Team
TG
02/14/2025
TINA G.
United States
No real change
I have been taking these products for about 6 months and honestly just don’t see much of a change except i feel like my hair may have grown a little. My bloating is still there, my bowel movements are the same. No real energy change.
02/18/2025
Heart & Soil Supplements
Hey Tina We're sorry to hear that you have seen the results you were hoping for. We'd be happy to help you dial things in a bit. While having nutrient-dense foods in our diet, like organ meats, is important sometimes we need to make positive dietary and lifestyle changes to really make a difference in our lives. We're curious to hear more about your situation, expectations, and health goals. We might be able to better assist you in achieving your desired results. Please feel free to reach out to our Health Success Team at radicalhealth@heartandsoil.co if you're interested in further support. We're happy to help! Best, The Heart and Soil Team
B
02/08/2025
Brad
United States
These supplements are helping my digestion.
TJ
02/06/2025
Tiffany J.
Life Changing
I had Covid in 2022 and ended up very ill and then in the ER. It destroyed my gut and immune health and mainstream doctors are clueless on how to fix these issues. The Gut & Digestion helped to build up my gut health. I've also taken many other Heart & Soil products. Most recently I had my 3rd child and suffered a large hematoma resulting in the need for a blood transfusion. I had no red blood cells when I left the hospital and again,my gut was destroyed. I have been on Gut& Digestion, Colostrum, Firestarter, Her Package (for hormonal balance), American Liver & Lifeblood. 2 weeks post birth on these supplements and my bloodwork was OPTIMAL (not "normal" but optimal!) I feel amazing- even with recovery and taking care of a newborn on little sleep. I'm a life long customer. Heart & Soil is life changing and I'll continue to tell everyone I know!!
Shop by health goals
Shop all Health Goals
GET EXPERT SUPPORT
Connect with our Health Success Team today for personalized guidance and support.
Connect with usGet weekly health insights delivered to your inbox so you can radically improve your health
Join 155,000+ Subscribers
180,582+ Customers
Free US Shipping on $80+